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We are a research group working in the area of Synthetic Organic Chemistry.
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Group Events and News
23/2 Our method for peptide synthesis using only DMAP, Br-CCl3 and a touch of Sun light is accepted for publication in Angewandte Chemie! Congratulations to Abhaya who started this research, Galit who did all the computational work as well as Sourav, Andrii, Jonatan, and Ortal. This work was a collaboration between our group and our dear friend Yoav Eichen's group at the Technion.
1/1 A new Year and welcome to new Ph.D. student Abhijit Kashid!
16/12 Group Hanukkah party! We welcomed our newcomers, Raz, Jonatan and Ortal to the group and also said farewell to Sourav who is leaving after three years as a Postdoctoral Fellow in the group. Check out the pictures on Twitter.
1/12 Jonatan Rahamim And Ortal Dorfman join the group for their Ph.D. studies. Welcome and lots of success!
25/11 Congratulation to Sourav on his paper on Solar light mediated benzylic oxygenation now out in JOC!
AMS is made Vice Dean for Research effective from 15/11
Raz Strugano joins us for her M.Sc. Welcome to the group!
Our paper on the the Umpolung alfa- functionalization of enones via a Morita-Baylis-Hillman type reaction is accepted for publication in Angewandte Chemie as a HOT paper. Congratulations to Shlomy, Sourav, Gulab and Raja for this extraordinatry achievement!
Atul's paper on the synthesis of vinyl indoles is published in Organic Letters. Congratulations!
/3-/4 AMS serves as a consultant on the COVID-19 crisis also partcipating in disinfection missions in order to provide safety for the public
Lenin's giant chapter on nitroxide chemistry is submitted to the editors. Fingers crossed!
AMS presents a seminar at the Hebrew University Institute of Chemistry
Atul's and Sourav's paper on Azido-Enolonium Species is published in Organic Letters. Congrats!
Goodbye to postdoc Dr. Abhaya Mishra who is leaving us to take up a new position in the Weaser group at EPFL. Best of luck Abhaya!
29. December Congratulations to Shlomy and his bride Einav on their marriage!
AMS present a seminar at the Weizmann Institute of Science
2. December. Shlomy passes his Ph.D. exam with flying colors. Congratulations Dr. Shlomy Arava!
We are now hiring. We are looking for two postdoctoral fellows and two Ph.D. students to join our research team. Submit your application to
Group lunch to say goodbye to Shimon and Atul that are leaving the group. Lots of success to both!
AMS is the recipient of a grant from the Council of Higher Education - Planning abd Budgeting Committee. This grant will complement the ISF grant for buying a High Resolution Mass Spectrometer we won last year with Flavio Grynszpan and Miki Montag and is meant to pay the salary for the operator for the next four years.
Sourav's patent on Benzylic C-H oxidation is filed. Now time to submit the paper. Congrats to Sourav
This month Raja Kapanaiah joined us for his Ph.D. and Angelika Gorianov and Shelly Paxton joined us for undergraduate research projects. Welcome and lots of success to all 3.
Our paper on the first ever alfa-deuterium nitroxides is accepted for publication in Organic & Biomolecular Chemistry
AMS present a lecture at the European Symposium on Organic Chemistry (ESOC) in Vienna
AMS is the recipient of an Israel Science Foundation Individual Research Grant. This grant will support our research on Umpolung of ketones/Enolonium Species for the next four years
Shlomy presents his final Ph.D. seminar
AMS will present a short talk at the ISySyCat conference
AMS will present a lecture on Enolonium chemistry at the ESOC meeting in Vienna
Gulab leaves us to look for new opportuntites in India. We are grateful to Gulab for providing us with a good atmosphere and for his many contributions to the group!
Shlomy, Abhay, Gulab and Atul presents posters and AMS chairs a session at the Israel Chemical Society Conference.
Shimon passes his Ph.D. defense. Congratulations Dr. Maksymenko!
AMS is the recipient of a grant from the Ministry of Defense/MAFAT
Shimon gives his final seminar and is off to write his thesis
AMS Promotion to the rank of Associate Professor is approved by the Ariel U. promotion committee
Sagi Sevilia a Ph.D. student from the Yoav Eichen group collaborating with us, delivers an energetic final seminar at the Technion.Congrats to Sagi.
AMS presents a seminar at Tel Aviv U. School of Chemistry
Hila Toledo passes her final Ph.D. exam. Congratulations to Hila
Our contribution to the Special Issue of the Journal of Coordination Chemistry in honor of Dan Meyerstein is published online. Congrats to Abhaya, Galit, Irit and the Xray scientist Natalie Fridman. Thank you to the Yoav Eichen group and especially Yoav for the collaboration.
In the last few years, we have characterized and used electrophilic enolonium species in reactions such as arylation, alkylation, allylation, prenylation, amination, azidation, and enolate cross-couplings. Want to carry out one of these reactions or develop your own? Here is a detailed protocol to try it out (link also available from the Publications page). Happy Enolate Umpolung!
Our ISF Institutional grant application for funding a HRMS has been approved. 1.85 Million Shekels including the matching funding from the University. Congratulations to our co-PIs Flavio Grynszpan and Michael Montag and to Ariel University which will receive its first HRMS. This is a great step forward in getting faster and better results and the instrument will serve multiple departments and researchers across the University.
After two highly successful years and being instrumental in setting up the group at Ariel U. Keshab leaves the group for a second postdoc with McGrath at the University of Arizona, Tucson. We wish Keshab best of luck in his future endeavors. Check out pictures from his goodbye Picnic on our Twitter and Facebook pages.
Hila gives her final seminar. Time to write that thesis!
1-4. July AMS presents a lecture and Shimon a poster at the excellent International Conference on Hypervalent Iodine organized by Thomas Wirth at Cardiff University.
21. June Our group together with those of Itay Benhar and Nir Osherov at Tel Aviv University are the winners of a KAMIN grant to further research our antifungal Amphotericin B derivatives with the goal of making them into clinically useful medicines.
AMS presents a lecture and two posters at the EuCHeMS Conference on Organic Free Radials in Marseille.
Our BJOC paper on cross-coupling of dissimilar enolates via enolonium species is one of the most accessed papers of the journal.
Irit Cohen receives her Ph.D. certificate to become the groups 4th Ph.D. Congratulations to Irit.
Yuriy Lipisa passes his Ph.D. proposal exam. Congrats to Yuriy!
Our BJOC paper is online
Our protocol for the preparation and use of enolonium species is accepted for publication in JoVE. Congratulations to Shlomy, Shimon, Keshab, Atul, Gulab, and Yuriy!!
Our paper on the cross-coupling of ketone enolates to give unsymmetrical 1,4-diketones is accepted for publication in Beilstein Journal of Organic Chemistry. Congratulations to Keshab, Shimon and Gulab!!
Our paper on the alfa-azidation and azolation of ketones via enolonium species is accepted for publication in The Journal of Organic Chemistry. Congratulations to Atul, Gulab, Keshab, Shimon and Yuriy!!
Irit Cohen defends her thesis to become the group's 4th Ph.D. Congrats to Irit!
AMS and Yoav Eichen ares the recipients of a MAFAT research grant
Our paper on Umpolung Arylation of Ketones via Enolonium Species is published in Organic Letters. Congratulations to Shimon, Keshab, Gulab, Atul and Yuriy!! Go to the publication page and click on the link to read.
Our Angewandte paper on Enolonium Species is now an "ISI Highly Cited Paper" marking it as a being in top 1% cited papers in Chemistry published this year. The distinction is given according to measurements by the ISI and noted on the Web of Science
AMS presents the group's research on Umpolung using Enolonium Species at the International Symposium on Synthesis and Catalysis (Evora, Portugal). Report and pics on our FB and Twitter accounts. Other Israeli speakers are Prof. Moshe Portnoy (TAU) and Prof. David Milstein (WIS).
AMS presents the group's Umpolung work at the EFMC-ASC'17 conference in Vienna heck out pictures on our FB and Twitter page.
Our paper with the Eichen lab is accepted for Publication in Chemical Communications.
Congrats to Irit, Abhaya, Galit, Mauricio, and Rachel. Cheers to Yoav for working with us.
Hila, Keshab, Shimon, Atul, Gulab and Yuriy present the group's work on Nitroxides and Umpolung at the 14th Annual Meeting of The Medicinal Chemistry Section - Israel Chemical Society.
29. April Lenin Kumar joins us for his Ph.D. Welcome and wishes for lots of success
25. April Dr. Sourav Santra joins the group as a Postdoctoral Fellow. Welcome!
Our paper has on Cu/TEMPO catalysis been highlighted in ChemistryViews.
Click Here to read.
Our paper on the identification of the intermediate in hypervalent iodine mediated α-functionalization of enolates is published in Angewandte Chemie. Congratulations to Shlomy, Jay, Shimon and Keshab! Also congrats and thank you to our collaborators Dr. Mark Iron and Dr. Peter Fristrup!
Thank you to Professor Dieter Seebach for suggesting the term "Enolonium Species" for these intermediates.
Go to the publications page and click on the link to read at Angewandte Chemie Early View.
Our paper on the Mechanism of Cu/TEMPO catalyzed aerobic oxidation of alcohols is named a HOT paper in Chemistry a European Journal
Prof. Yoav Eichen (Technion) and AMS are the recipients of a research grant from MAFAT.
Our Chemistry A European Journal paper is online as an "accepted article"! Go to the Publications page and click on the link to read.
Our paper on the Mechanism of the TEMPO/Cu(II) catalyzed aerobic oxidation is accepted for publication in Chemistry a European Journal.
Dr. Atul More joins our group as a Postdoctoral Scholar. Welcome!
Yuriy joins our group as a Ph.D. student. We wish him lots of success!
Jay Kumar leaves the group to take up a postdoctoral position in the group of Prof. Jung-Mo Ahn at the University of Texas at Dallas. We wish him the best of luck in his future career
Our new webpage is live, but still very much under construction
Dr. Gulab Pathe joins the group. Welcome!
AMS presents a lecture at Novartis
Yuriy Lipisa joins our group for a summer research internship. Welcome!
AMS and Shimon presents at the 5th International Conference on Hypervalent Iodine
Dr. Keshab N. Parida joins the group. Welcome!!
AMS attends the Burgenstock Conference and presents a seminar at EPFL
Our paper on nontoxic, watersoluble Antifungal Amphotericin B derivatives is highlighted by QuantaBioDesign
Our Umpolung Paper in Organic Letters is highlighted at the Organic Chemistry Portal
This paper remains the most highly cited research paper published from the Faculty of Chemistry in the last 18 months
Our group moves to Ariel U.
9-10. Feb. Our group presents 3 posters and AMS gives a talk at the 81st Israel Chemical Society Meeting
27. Jan. Our J. Med. Chem. paper is now online
Our collaborative work with the Benhar and Osherov groups (TAU) on antifungal, non-toxic, watersoluble, AMB derivatives is accepted for publication in the Journal of Medicinal Chemistry. The compounds have also been patented.
5. Jan. Sveta succesfully defends her thesis to become the groups 3rd Ph.D. Congratulations Dr. Shneider!!
30. Dec. Tal Liphits defends her thesis and becomes a Master of Science.
Our collaborator on paper No 22, Rami Batrice (Eisen group) passes his Ph.D. Exam. Congrats to Dr. Batrice!
Spanning the Globe in a fortnight: AMS presents talks at Tianjin U. (China), Queen's U. (Belfast) and Bar Ilan U. (Israel)
The entire group presents at the 6th EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry
AMS wins the Thieme Prize for "Best Poster Representation"
Hila Toledo wins the "European Federation for Medicinal Chemistry Best Poster Prize"
Congratulations to Hila!
2. Nov, AMS presents a seminar at Ben Gurion University
25. Oct. AMS gives a talk at Tel Aviv University
Our OBC paper is designated a HOT PAPER by the reviewers.
Our alfa-hydrogen nitroxide paper is online in the final version on the
A paper on our new nitroxides is accepted for publication in Organic
& Biomolecular Chemistry. Congratulations to Hila, Michal, Sukanta,
Boris, Mark, Natalia and Linda!
A patent application on new antifungal drugs is filed (collaboration
with Asaf Dergachev, Nir Osherov and Itai Benhar of Tel Aviv U.)
Sveta presents a poster at the European Symposium on Organic Chemistry
Our ChemCatChem paper on Nitroxide/Cu catalyzed aerobic oxidation of
alcohols is highlighted in ChemInform
AMS is the recipient of an Israel Science Foundation Individual
Our Asymmetric Umpolung paper in OBC is highlighted in ChemInform
AMS demonstrates the power of chemistry to third-graders
Prof. Yoav Eichen and AMS are the joint recipients of a major
government research grant!
AMS presents talks at Ariel U. and Hebrew U. Jerusalem
25. May Our Organic Letters Umpolung paper is selected as paper of the
week on the TCI website:
Our Organic Letters Umpolung paper is highlighted in ChemInform
22. May AMS presents a seminar at RWTH Aachen
21. May AMS presents a seminar at Universite Libre de Bruxelles
11. May Sveta Shneider presents her final research seminar. COngrats to
Our Tetrahedron Asymmetry paper is one of the 20 most downloaded papers
of the last 90 days!
The Israel Chemical Society running team participates in the 220 km
Mountain to Valley Relay Race in Northern Israel.
Yaniv Bouhadana (Bar Ilan U.), Itay Gdor (Hebrew U.) and AMS captain
and organize the teams with Paual Lam Haim of the ICS. Thank you to
Rotel Chemicals and Adhesives for their sponsorship!
AMS presents a poster at the famed Burgenstock Conference
Our work on Nitroxides is highlighted in Jerusalem Post:
AMS runs the Technion Challenge 2015
Tom passes his M.Sc. thesis defence. Congrats to Tom!
Group picnic/flower-watching hike in honor of our new Ph.D. graduates
Our Asymmetric Umpolung paper in Organic and Biomolecular Chemistry is
chosen as a HOT paper!
Our ChemCatChem paper on aerobic oxidation of alcohols using our IAPNO
radicals is online.
A link to the paper is provided on our Publications page.
Michal successfully defends her Ph.D. thesis to become the groups
Congratulations to Dr. Amar!
Shlomit passes her thesis defence to become the group's first Ph.D.
Congratulations Dr. Avidan!
4. Mar. Jay Invites the group for lunch at his place. Delicious!
1. Mar. Shlomy joins the group for his Ph.D. Welcome!
25. Feb. Group lunch on the occasion of Tom leaving Haifa
19. Feb. AMS presents at a mini-symposium at Teva together with Prof.
Bob Waymouth (Stanford U.)
17. Feb. Sveta, Jay, Tom, Hila, and Shimon present posters at the 80th
Israel Chemical Society Meeting Our umpolung paper in Organic Letters
is highlighted in SynFacts
Our paper "Design Concept for alfa-Hydrogen Substituted Nitroxides" is
published in leading general science journal Nature Communications!
Congratulations to Michal (what a way to finish a Ph.D.!), Sukanta, our
dear collaborator Mark Iron (WIS), Hila, Boris, Linda (WIS), Mark
Botoshansky (Zichrono Le'vracha), and Natalia.
A link to the online paper is provided on the Publications page. Enjoy
Our Umpolung paper in Organic Letters has been downloaded more than a
thousand times since publication!
This makes it one of the most downloaded Organic Letters in January. A
paper is accepted for publication in ChemCatChem
Congrats to Sukanta, Jay, Michal, Hila and Rami!
18. Jan. Tom Targel presents his M.Sc. research seminar, Congrats to
Our Tetrahedron Asymmetry paper is online. Go to the Publications page
to read it!
Our group's paper on asymmetric umpolung alkylation is accepted for
publication in Organic & Biomolecular Chemistry.
Congratulations to Tom, Jay, Sveta, Sukanta, Natalia and Shimon! The
paper is online as a "just accepted paper".
Our Umpolung paper in Organic Letters is online!
Our group will present four posters, highlighting some of our recent
publications, at the upcoming Israel Chemical Society Meeting
Sveta's and Jenya's paper on oxidative umpolung alkylation of ketones
is accepted for publication in the premier organic chemistry journal
Congratulations to Sveta and Jenya!
Congratulations and Thank You to friend and collaborator Professor
Peter Fristrup (Technical University of Denmark)!
Our ACS Catalysis paper is online!
Follow the link from the Publications page to read it.
Hari's and Ravi's paper on a new family of axially chiral ligands is
accepted for publication in Tetrahedron Asymmetry. Congrats to Hari and
AMS presents talks at Ben Gurion University of the Negev (7. Dec.) and
the Hebrew University of Jerusalem (15. December).
Shlomit's and Hari's paper detailing the development and mechanistic
study of an asymmetric catalytic aza-Michael reaction is accepted for
publication in the prestigious journal ACS Catalysis.
Congratulations to Shlomit and Hari!!
27. AMS presents a talk at the Technion. October
20. Shlomit Avidan-Shlomovich, the group's first Ph.D. student,
presents her final research seminar. Congratulations to Shlomit for a
job well done!
27. Michal Amar, the group's second Ph.D. student, presents her final
Congratulations to Michal!!
28. AMS presents a seminar at the Weizmann Institute of Science.
Dr. Sukanta Bar leaves the group for a second postdoc with Prof.
Schindler at the University of Michigan Ann Arbor.
We wish Sukanta the best of luck and success. Thank you for being a
part of the group and contributing to a good atmosphere and to the
science in the group!
Dr. Ravi Vavilala leaves the group. We wish Ravi all the best!
3. AMS presents a seminar at U. Michigan Ann Arbor
5. AMS presents a seminar at the University of Utah
8. AMS gives a talk at UC Santa Cruz
10. AMS presents a special seminar at UC Berkeley
13-26. AMS is a Liebigs College Visiting Professor teaching a course
and presenting a seminar at Justus Liebigs University Giessen
Shimon Maximenko joins the group for his Ph.D. Welcome!!
27. Jul-2. Aug. Shlomit, Michal and AMS present the group's work
at the GRC on Stereochemistry in Synthesis, Catalysis, and Chemical
29.June - 4. July. AMS presents a lecture at the EuChems Conference
on Organic Free Radicals in Prague.
23-24. Shlomit, Michal, Hila and AMS present at the 12th Ann. Meeting
of the Medicinal Chemistry Section of the ICS at the Weizmann
Institute of Science
Hila Toledo has been awarded the Prize for Best Student Abstract. She
will present her lecture on the first day of the meeting, Monday the
23rd of June at 15.20.
21-22. Student Day at the Technion with Ivri Lieder, HaDag Nachash,
Aviv Geffen, Infected Mushroom and many other artists
15. May AMS presents a seminar at the University of Munster
12.May AMS presents a seminar at the University of Gottingen
8. May Faculty Karaoke Party
4. May Tal Lipshits presents her Final M.Sc. seminar at the Faculty.
Congrats to Tal!
25. March AMS presents a seminar at Aarhus University. Denmark.
26. March AMS presents a seminar at the DTU, Denmark.
13. New pictures page
4. AMS presents a lecture at the 79th Israel Chemical Society Meeting
in Tel Aviv
Michal Amar presents a Lecture at the Schulich Symposium at the
Technion. Several other group members presented posters.
Dr. Jayprakash joins the groups as a Schulich Postdoctoral
Dr. Hari Ghosh leaves the group for a postdoc in Japan.
Tom Targel joins the group for his M. Sc. Welcome
The group goes on a trip around Agamon HaHula Check out the Pics
Sveta and Evgeni present a poster at the Israel Chemical Society
A PCT application is filed.
Dr. Sukanta Bar travel's to India for his Wedding.
September Dr. Vavilala joins the group Welcome
Our paper on Direct Oxidation of Alddehydes to Mixed Anhydrides and
one-pot conversion to Esters and Amides is accepted for Publication in
Chemical Communications (2013 Young Ivestigator Issue).
Congratulations to Hila, Evegeni and Adi!
AMS shows the flag at the 4th EuCheMs Young Investigator Workshop in
Vienna AND the 4th EuCheMs Conference in Prague
Sabrina Batke joins us for a two month IAESTE internship, Welcome July
Our paper on the Oxidative Dimerisation of Alcohols using TEMPO has
been accepted for publication in Synlett.
Congratulations to Adi, Hila and Evgeni
Michal Amar wins a Schulich Doctoral Fellowship. Congratulations!!
The group shows the flag at the Israel Chemical Society.
Hila and Michal presents posters and AMS presents a lecture
Dr. Sukanta Bar joins us as a Schulich Postdoctoral Fellow. Welcome!
Tal Lipshits joins us for her M.Sc. degree Welcome!
July AMS is the recipient of an Israel Science Foundation Bikura
Enrico Fantoni from Imperial College London Joins us a a IAESTE summer
research student. Welcome
After a two year delay the group finally moves into its newly renovated lab and student office on the
March Having enjoyed his time as an undergraduate research student in
the group Evgeni Piseravski decides to join us for his M.Sc.
Our GCMS and HPLC are now online
Dr. Harisadhan Ghosh joins us as a Schulich Postdoctoral Fellow.
The review" "Probing the Biology of Natural Products: Molecular Editing
by Diverted Total Synthesis" written by AMS and Erick M. Carreira
appears in Angewandte Chemie.
Half the group does an outing to the Linkin Park concert in Tel Aviv
A new semester begins
Welcome to our two new group members: Hila Toledo who will be studying
for her M.Sc. and Sveta Schneider who will be pursuing her Ph.D.
Congratulations to Shlomit, Husband Doron and their son Gilad on the
birth of their baby boy Roye.
AMS is honored with the Chaya Career Advancement Chair
"Silver in Organic Synthesis" edited by Professor Michael Harmata hits
the shelves. AMS and Erick Carreira has cowritten one of the chapters
in this book. It is available directly from Wiley or from several
AMS is the recipient of an Israel Science Foundation Individual Grant
and an ISF Equipment Grant for New Faculty
AMS is the recipient of a Young Scientist research grant from the
German-Israeli Foundation for Scientific Research and Development June
A review written by Astrid Volmer, AMS and Erick M. Carreira and
covering Amphotericin B studies from 1955 to 2009 appears in Natural
Product Reports (AMS postdoctoral work).
Welcome to our newest member Michal Amar who will be pursuing her Ph.D.
Also welcome to our spring semester project student Evgeni Piseravsky.
Kate Tishin Joins the Group for her M. Sc. Welcome!
Adi Abramovicz leaves the group to join Taro Pharmaceuticals .
Congratulations to Adi and best of luck.
Shlomit Avidan Joins the Group for ther Ph.D. Welcome!
Our Solvent System is installed to the benefit of lab safety and easy
access to dry solvents.
Tal Shvartzfeld joins the group for her M.Sc. and gets married.
Congratulations to Tal Liphshits and her Husband Stas July 2009
Agelika Sokolow joins the group. She will start research
21st of June
A full account of the synthesis and biophysical studies on
35-deoxy-amphotericin B (Dr. Szpilman postdoctoral work with Professor
Carreira at the ETH) is published in Chemistry a European Journal
7th of April 2009
ite is live!
1st of March 2009
Dr. Adi Abramovich joins the group
26th of February 2009
A paper describing parts of Dr. Szpilman's postdoctoral work with
Professor Carreira at the ETH is published in Organic Letters
4th of February 2009
The group is founded